Sanger Heart & Vascular Institute physicians are committed to actively participating in global and national clinical trials to develop innovative approaches for treating cardiovascular disease.

Leading-edge Cardiovascular Research

Our physicians collaborate, using their expertise to create pioneering heart procedures and programs.

Frank Arko, MD, and a team of vascular specialists were the first in the world to perform an in-human branched stent graft implantation specially designed to repair thoracic aortic aneurysms that encroach on the left subclavian artery. This procedure was part of an FDA-approved initiative to encourage early-stage research on innovative devices.

Michael Rinaldi, MD, was one of the first interventional cardiologists in the world to perform a procedure using a specially-designed device to correct mitral valve regurgitation.

Ongoing research into the treatment of refractory hypertension has resulted in the establishment of a refractory hypertension center led by Richard E. Brown, MD.

Sanger Heart & Vascular Institute physicians are committed to actively participating in global and national clinical trials to develop innovative approaches for treating cardiovascular disease.

Ongoing Cardiovascular Research

Transcatheter Mitral Valve Repair  (COAPT Trial) – A multicenter, industry-sponsored clinical trial, evaluating the use of a device to repair moderate-to-severe functional mitral regurgitation in patients who are high-risk candidates for conventional surgery.  

Stem Cell Therapy for Refractory Angina (RENEW Stem Cell Study) – A randomized controlled trial investigating the use of stem cells for the treatment of chest pain due to blockages in the heart. Patients are treated with autologous stem cells harvested from the patients’ own blood for the purpose of growing new blood vessels in the heart. 

Renal Denvervation for Refratory Hypertension (SIMPLICITY Trial) This trial tests the safety and efficacy of a novel method to treat patients who have uncontrolled hypertension even with the use of medications. It involves radiofrequency pulses to deactivate nerves near the kidneys, which may result in blood pressure reduction.  

Transcatheter Aortic Valve Replacement (SURTAVI Study) A multicenter, industry-sponsored clinical trial that compares the use of an investigational valve replacement system with conventional open heart surgery for patients with severe narrowing of the aortic valve who are at moderate risk for conventional surgery.

Sanger Heart & Vascular Institute Physician Abstracts, Publications and Presentations

Abstracts

Arko FA, Hurd AH, Nussbaum T, Boyes C, Lalka SG, Roush TS. Comparison of Acute Versus Chronic Dynamic Intimal Flap Movement in Stanford Type B Aortic Dissections (ATBD) and the Effects of Thoracic Endovascular Stent Grafting

Cassidy LM, Edwards NC, Hebert L, Franklin W, Downey WE. Lipid Management of Ischemic Vascular Patients: A Performance Improvement Team Approach. CHS Quality Day of Sharing, Charlotte, NC, July 2012.

Cassidy LM, Liebner K, Magyar R, Humhrey AD, BH, Rose GA, Kowalchuk GJ, Rinaldi MJ, Haber RH, Cedarholm JC, Downey WE. Efficacy and Cost Savings Realized Through Validation of a Tool to Identify Low-risk STEMI Patients Not Requiring CCU Care. American Heart Association Quality of Care & Outcomes Research Scientific Sessions, Atlanta, GA, May 2012.

Cassidy LM, Liebner K, Magyar R, Humphrey AD, Wilson BH, Rose GA, Kowalchuk GJ, Rinaldi MJ, Haber RH, Cedarholm JC, Downey WE. 19. Efficacy and cost savings realized through validation of a tool to identify low-risk STEMI patients not requiring CCU care. Presented at: American Heart Association’s Quality of Care & Outcomes Research Scientific Sessions (AHA QCOR), Atlanta, GA, May 2012

Fenner, D. Leahy, R. McCombs, T. Thomas, C. Woods, G. Bridging the Gap: Improving Patient Flow Through Service Line Integration. Presented at: CHS Quality & Service Sharing Day, Charlotte, NC, July 2012.

Garg A, Stuckey T, Brodie B, Cooper M, McAlhany C, Hansen C, Lane T, Cox D, Wilson BH. Spontaneous Coronary Artery Dissection as a Cause of Acute Coronary Syndrome: A Case Series and Management Options. Presented at: TCT 2012, Miami, FL. October 2012.

Gulati SK, Cuomo KA, Fenner DJ, McGarity GK. Use of a Heart Failure Device Diagnostics Coordinator. Presented at: AAHFN Annual Meeting 2012. Chicago, IL, June 2012.

Gulati SK, Cuomo KA, Fenner DJ, Harris DT. Use of an Inpatient Nurse Navigator to Coordinate Care for Heart Failure Patients. Poster Presentation AAHFN Annual Meeting 2012. Chicago, IL, June 2012.

Gulati SK, Fenner DJ, Harris DT. Heart Success Transitional Care for Patients with Heart Failure: Reducing Readmission by Improving Self-Management. Presented at: CHS Quality Day of Sharing, Charlotte, NC, July 2012.

Hurd AM, Boyes C, Nussbaum T, Madjarov J, Lalka SG, Roush TS, Arko FR. Evaluation of Dynamic Intimal Flap Movement in Acute Stanform Type B Aortic Dissection (ATBD) and the Effects of Thoracic Endovascular Stent Grafting. Presented at: AATS Annual Meeting 2013. Minneapolis, MN, February 2013.

Johnson TV, Rose GA, Fenner DJ. FOCUS: Appropriate Use of Cardiac Imaging Initiative. Presented at: AHA QCOR Scientific Sessions, Atlanta, Georgia, May 2012.

Johnson TV.  Cardiac Testing: Don’t Waste It! Presented at: Premier Breakthroughs Conference, Nashville, TN, June 2012.

Rinaldi MJ, Kirtane AJ, Parise H, Witzenbichler B, Weisz G, Neumann FJ, Metzger C, Henry T, Cox D, Duffy P, Brodie B, Stuckey T, Mazzaferri E, Cristea E, Mehran R, Stone GW. Impact of Point-of-Care Platelet Function Testing Among Patients with and Without Acute Coronary Syndromes Undergoing PCI with Drug-Eluting Stents: An ADAPT-DES Substudy. Presented at: ACC 2012, Chicago, IL, March 2012.

Rinaldi MJ, Kirtane AJ, Parise H, Witzenbichler B, Weisz G, Neumann FJ, Metzger C, Henry T, Cox D, Duffy P, Brodie B, Stuckey T, Mazzaferri E, Cristea E, Mehran R, Stone GW. Does Platelet Function Testing Add Significant Incremental Risk Stratification to Unselected Patients Undergoing DES Implantation? The ADAPT-DES Study. Presented at: ACC 2012, Chicago, IL, March 2012.

Stone GW, Witzenbichler B, Weisz G, Rinaldi MJ, Neumann FJ, Chavez I, Metzger C, Cox D, Duffy P, Stuckey T, Mazzaferri E, Parise H, Brodie B. A Large-Scale Prospective Registry to Determine the Relationship Between Aspirin and/or Clopidogrel Hyporesponsiveness and General Platelet Reactivity to Stent Thrombosis After Drug-Eluting Stent Implantation: Thirty-Day Results from the ADAPT-DES Study. Presented at: TCT 2011, San Francisco, November 2011.

Wilson BH, Humphrey A, Haber R, Downey W, Cedarholm J, Kowalchuk G, Rinaldi MJ, Miller D, Sarafin J, Collier K, Garvey J. Initial Ambulance Transport of ST-Elevation Myocardial Infarction (STEMI) to Rural Hospitals Leads to Better Door In-Door Out and First Door to Balloon Reperfusion Times within 90 Minutes. Presented at: ACC 2012.

Witzenbichler B, Maehara A, Weisz G, Neumann FJ, Rinaldi MJ, Metzger C, Henry T, Cox D, Duffy P, Brodie B, Stuckey T, Mazzaferri E, Xu K, Mehran R, Praise H, Mintz GS, Stone GW. Use of IVUS reduces stent thrombosis: Results from the prospective, multicenter ADAPT-DES study.Presented at: TCT 2012, Miami, FL, October 2012.

Publications

Adams CD, Bridges CR, Casey D, Ettinger SM, Fesmire FM, Gamiats TG, Lincoff MA, Peterson ED, Philippides GJ, Theroux P, Wenger NK, Zidar JP. 2012 ACCF/AHAFocused Update (on Oral Antiplatelets) of the Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update). J Am Coll Cardiol. 2011; 57(19):1920–59.

Anderson, JL, Adams CD, Antman, EM, Bridges, CR, Califf RM, Casey, DE Jr, Chavey WE II, Fesmire, FM, Hochman JS, Levin TN, Lincoff MA, Peterson ED, Theroux P, Wenger NK Wright RS. 2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice GuidelinesCirculation 2011; 123(18): e426-579.

Arko FR, Jordan WD Jr, Robaina S, Arko MZ, Fogarty TJ, Makaroun MS, Verhagen HJ. Interdisciplinary and translational innovation: the endurant stent graft…from bedside to benchtop and back to bedside. J Endovasc Ther. 2011 Dec;18(6):779–85.

Arko FR, Nussbaum T, Lalka SG, Holleman J, Roush TS. The Endurant Stent Graft: Advantages from Lessons Learned. Endovasc Today 2012: (Suppl. 3-6).

Arko FR 3rd, Murphy EH, Boyes C, Nussbaum T, Lalka SG, Holleman J, Roush TS. Current status of endovascular aneurysm repair: 20 years of learning. Semin Vasc Surg. 2012 Sep;25(3):131–5.  

Bridges CR, Dandolu R. Cardiac Surgery. In Ferdinand K (ed). Educational Review Manual in Cardiovascular Disease. Connolly Graduate Medical Publishing, 2011.

Byrne JG, Rezai K, Sanchez JA, Bernstein RA, Okum E, Leacche M, Balaguer JM, Prabhakaran S, Bridges CR, Higgins RSD. Surgical Management of Endocarditis: The Society of Thoracic Surgeons Clinical Practice Guideline. Ann Thorac Surg 2011; 91:(6) 2012–2019.

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Caughey MC, Hinderliter AL, Jones SK, Shah SP, Ataga KI. Hemodynamic characteristics and predictors of pulmonary hypertension in sickle cell disease. Am J Cardio. 2012;109(9):1353–1357.

Dixon JA, Gorman RC, Stroud RE, Mukherjee R, Meyer EC, Baker NL, Morita M, Hamamoto H, Ryan LP, Gorman JH 3rd, Spinale FG. Targeted regional injection of biocomposite microspheres alters post-myocardial infarction remodeling and matrix proteolytic pathways. Circulation. 2011;124:S35–45.

Fargnoli AS, Katz MG, Steuerwald N, Ghosh S, Richardville KC, Hillesheim R, Williams RD, Kohlbrenner E, Stedman HH, Hajjar RJ, Bridges CR. Cardiac Surgical Delivery of the Sarcoplasmic Reticulum Calcium ATPase Rescues Myocytes in Ischemic Heart Failure. Ann Thorac Surg, 2012;96(2): 586–95.

Fargnoli AS, Katz M, Yarnall C, Sumaroka M, Stedman HH, Rabinowitz J, Koch W, Bridges CR. A Pharmacokinetic Analysis of Molecular Cardiac Surgery with Recirculation Mediated Delivery of βARKct Gene Therapy: developing a quantitative definition of  the therapeutic window. J. Card. Fail. 2011;17(8):691–699.

Feldman T, Foster D, Glower DG, Kar S, Rinaldi MJ, Fail, PS, Smalling RW, Siegel R, Rose GA, Engeron E, Loghin C, Trento A, Skipper ER, Fudge T, Letsou GV, Massaro JM, Mauri L. Percutaneous Repair or Surgery for Mitral Regurgitation. NEJM. 2011; 364:1395–406.

Fernando HC, Jaklitsch MT, Walsh GL, Tisdale JE, Bridges CR  Mitchell JD, Shrager JB. Executive Summary of the Society of Thoracic Surgeons Practice Guideline on the Prophylaxis and Management of Atrial Fibrillation Associated with General Thoracic Surgery. Ann Thorac Surg. 2011; 92:1144–152.

Foster E, Kwan D, Feldman T, Weissman NJ, Grayburn PA, Schwartz A, Rogers JH, Kar S, Rinaldi MJ, Fail PS, Hermiller J, Whitlow PL, Herrmann HC, Lim DS, Glower DD; EVEREST Investigators. Percutaneous Mitral Valve Repair in the Initial EVEREST Cohort: Evidence of Reverse Left Ventricular Remodeling. Circ Cardiovasc Imaging. 2013 Jul 1;6(4):522–30.

Gussak I, Antzelevitch C, Wilde A, Powell B, Ackerman M, Shen W, editors. Electrical Diseases of the Heart, 2nd Edition. Springer. 2008.

Herlong JR. Pediatric Echocardiography.  In Coley B, Slovis TL, Frush DP, Bulas DI, et al, ed. Caffey’s Pediatric Diagnostic Imaging, 12th edition. Philadelphia, PA: Mosby; 2012. 

Herlong JR.  Introductory Embryology.  In Coley B, Slovis TL, Frush DP, Bulas DI, et al, ed. Caffey’s Pediatric Diagnostic Imaging, 12th edition. Philadelphia, PA: Mosby, 2012. 

Hillis LD, Smith PK, Anderson, JL, Bridges CR, Byrne JL, Cigarroa, JE, DiSesa VJ, Hiratzka, LF, Hutter AM, Jessen,  ME, Keeley EC, Lahey S, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD. 2011 ACCF/AHA Guidelines for Coronary Artery Bypass Surgery. J. Am. Coll Cardiol. 2011;58(24):e123–210.

Hillis LD, Smith PK, Anderson, JL, Bridges CR, Byrne JL, Cigarroa, JE, DiSesa VJ, Hiratzka, LF, Hutter AM, Jessen,ME, Keeley EC, Lahey S, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD. 2011 ACCF/AHA Guidelines for Coronary Artery Bypass Surgery. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;124 (23):e652–735.

Jassar AJ, Ford PA, Haber HL, Isidro A, Swain JD, Bavaria JE, Bridges CR. Cardiac Surgery in Jehovah's Witness Patients: 10-Year ExperienceAnn of Thorac Surg. 2012;93:19–25.

Jneid H, Anderson JL, Wright RS, Adams CD, Bridges CR, Casey DE, Jr., Ettinger SM, Fesmire FM, Ganiats TG, Lincoff AM, Peterson ED, Philippides GJ, Theroux P, Wenger NK, Zidar JP. 2012 ACCF AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update):  A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2012; 60(7):645–81.

Jneid H, Anderson JL, Wright RS, Adams CD, Bridges CR, Casey DE Jr., Ettinger SM, Fesmire FM, Ganiats TG, Lincoff MA, Peterson ED, Philippides GJ, Theroux P, Wenger NK, Zidar JP. 2012 ACCF AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina Non-ST-Elevation Myocardial Infarction Updating the 2007 Guideline and Replacing the 2011 Focused Update): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2012; Aug 14;126(7): 875–910.

Jollis JG, Al-Khalidi HR, Monk L, Roettig ML, Garvey JL, Aluko AO, Wilson BH, Applegate RJ, Mears G, Corbett CC, Granger CB; Regional Approach to Cardiovascular Emergencies (RACE) Investigators. Expansion of a regional ST-segment-elevation myocardial infarction system to an entire stateCirculation. 2012; Jul 10;126(2):189–95. Epub 2012 Jun 4.

Johnson T, Symanski J, Patel S, Rose G. Improvement in the Assessment of Diastolic Function in a Clinical Echocardiography Laboratory Following Implementation of a Quality Improvement Initiative. J Am Soc Echocardiogr. 2011; Nov;24 (11):1169–1179.

Katz MG, Fargnoli AS, Swain JD, Tomasulo CE, Ciccarelli M, Huang ZM, Rabinowitz JE, Bridges CR.  AAV6-BARKct gene delivery mediated by molecular cardiac surgery with recirculating delivery (MCARD) in sheep results in robust gene expression and increased adrenergic reserve. J Thorac Cardiovasc Surg. 2012; Mar;143(3): 720–726.

Katz MG, Fargnoli AS, Pritchette LA, Bridges CR. Gene delivery technologies for cardiac applications. Gene Ther. 2012;19(6):659–669.

Katz MG, Fargnoli AS, Pritchette LA, Bridges CR.  MCARD-Mediated Gene Transfer of GRK2 Inhibitor in Ovine Model of Acute Myocardial Infarction. Gene Delivery Technologies for Cardiac Applications. Gene Ther. 2012;Jun;19(6): 659–69.

Knowles M, Pellisar T, Murphy EH, Stanley GA, Hashmi AF, Arko MZ, Arko FR. In vitro analysis of type II endoleaks and aneurysm sac pressurization on longitudinal stent-graft displacement. J Endovasc Ther. 2011;Aug; 18(4):601–6.

Knowles M, Murphy EH, Dimaio JM, Modrall JG, Timaran CH, Jessen ME, Arko FR 3rd. The effects of operative indication and urgency of intervention on patient outcomes after thoracic aortic endografting. J Vasc Surg. 2011; Apr;53(4):926–34. Epub 2011 Jan 14.

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Lal BK, Roubin GS, Lutsep HL, Moore WS, Malas MB, Chiu D, Gonzales NR, Burke JL, Rinaldi MJ, Elmore JR, Weaver FA, Narins CR, Foster M, Hodgson KL, Shepard AD, Meschia JF, Bergelin RO, Voices JH, Howard G, Brott TG. Restenosis after Carotid Artery Stenting and Endarterectomy: A Secondary Analysis of CREST, A Randomized Control Trial. Lancet 2012, Vol 11, 755–763.

Littman L, Holshouser JW. Not so Fast: Acceleration-dependent or Mobitz type II Second-degree AV BlockAm J Med. 2012;125(10):967–970.

Maldonado TS, Dexter D, Rockman CB, Veith FJ, Garg K, Arko F, Bertoni H, Ellozy S, Jordan W, Woo E. Left subclavian artery coverage during thoracic endovascular aortic aneurysm repair does not mandate revascularization. J Vasc Surg. 2012 Sep 26. pii: S0741-5214(12)01584-4. doi: 10.1016/j.jvs.2012.06.101.

Mehta R, Love C. Management of Cardiac Leads Under Advisory: A Personalized Strategy. Online Publication Date: June 29, 2012.

Modrall JG, Rosero EB, Chung J, Arko FR 3rd, Valentine RJ, Clagett GP, Timaran CH. Defining the type of surgeon volume that influences the outcomes for open abdominal aortic aneurysm repair. J Vasc Surg. 2011;Dec;54(6):1599–604. Epub 2011 Oct 1.

Modrall JG, Timaran CH, Rosero EB, Chung J, Arko FA 3rd, Valentine RJ, Clagett GP, Trimmer C. Predictors of outcome for renal artery stenting performed for salvage of renal function. J Vasc Surg. 2011;Nov;54(5):1414–1421.e1; discussion 1420-1. Epub 2011 Jul 31.

Modrall JG, Rosero EB, Leonard D, Timaran CH, Anthony T, Arko FA 3rd, Valentine RJ, Clagett GP, Trimmer C. Clinical and kidney morphologic predictors of outcome for renal artery stenting: data to inform patient selection. J Vasc Surg. 2011;May; 53(5):1282–89; discussion 1289–90. Epub 2011 Feb 12.

Murphy EH, Stanley GA, Ilves M, Knowles M, Dimaio JM, Jessen ME, Arko FR 3rd. Thoracic endovascular repair (TEVAR) in the management of aortic arch pathology. Ann Vasc Surg. 2012;Jan;26(1):55–66.

Murphy EH, Dimaio JM, Jessen ME, Arko FR. Technique for branched thoracic stent-graft repair of a chronic type a aortic dissection in a patient with multiple prior sternotomies. J Endovasc Ther. 2011;Jun; 8(3):359–64.

Murphy EH, Arko FR  Commentary: A step closer to identifying patients at risk of developing clinically significant type II endoleaks. J Endovasc Ther. 2011;Jun;18(3): 306–7.

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Naunheim KS, Bridges CR, Sade RM. A Jehovah’s Witness Patient Who Faces Imminent Exsanguination Should Be Transfused. Ann Thorac. Surg.
Nov. 2011;92:1559–1564

Nazmul M, Cha YM, Lin G, Asirvatham SJ, Powell BDPercutaneous Pacemaker or Implantable Cardioverter Defibrillator Lead Removal in an Attempt to Improve Symptomatic Tricuspid RegurgitationEuropace. 2013;Mar;15(3):409–13.

Opotowsky AR, Perlstein T, Landzberg MJ, Colan SD, O’Gara PT, Brody SC, Ryan LP, Aranki S, Singh MN. A shifting approach to management of the thoracic aorta in bicuspid aortic valve. J Thorac Cardiovasc Surg. 2013;Aug;146(2):339–46.

Patel MR, Dehmer GJ. Hirshfeld JW, Smith PK, Spertus JA, Masoudi FA, Brindis RG, Beckman KJ, Chambers CE, Ferguson TB Jr, Garcia MF, Grover FL, Holmes DR, Klein LW, Limacher M, Mack MJ, Malenka DJ, Park MH, Ragosta M 3rd, Ritchie JL, Rose GA, et al. CF/SCAI/AATS/AHA/ASNC/HFSA/SCCT 2012 Appropriate Use Criteria for Coronary Revascularization Focused Update. J AM Coll Cardiol 2012; 59:9,857–81

Powell BD, Saxon LA, Bohmer JP, Day JD, Gilliam FR, Heidenreich PA, Jones PW, Rousseau MJ, Hayes DL.  Survival After Shock therapy in ICD and CRT-D Recipients According to Rhythm Shocked: ALTITUDE Survival by Rhythm Study. J Amer College Cardiol 2013, June 26.

Park HJ, Sung SW, Park JK, Kim JJ, Jeon HW, Wang YP. How early can we repair pectus excavatum: the earlier the better? Euro J CardioThorac Surg. 2012;Oct;42(4):667-721.

Pritchette LA, Carty AJ, Katz MG, Fargnoli AS, Kirsch J, Bridges CR. Swallow Syncope after Cardiac Surgery in a Sheep. Pritchette LA, Carty AJ, Katz MG, Fargnoli AS, Kirsch J, Bridges CR. Vet Surg. 2013;Sept13.

Robicsek F. Editorial Comment. Repair of pectus excavatum. Are we doing it better just to make it look better?  Euro J Cardiothorac Surg. 2012;41(5):1067-68. Improved Cardiopulmonary exercise function after modified Nuss operation for pectus excavatum. Euro J Cardiothorac Surg. 2012 41:1063–67.

Robicsek F, Padera RF Jr., Thubrikar MJ. Dilatation of the ascending aorta in patients with congenitally bicuspid aortic valves. HSR Proc Intensive Care Cardiovasc Anesth. 2012; 4(2):109–18.

Siegel RJ, Biner S, Rafique AM, Rinaldi MJ, Lim S, Fail P, Hermiller J, Smalling R, Whitlow PL, Herrmann Howard C, Foster E, Feldman T, Glower D, Kar S. The Acute Hemodynamic Effects of Mitraclip Therapy. J Am Coll Cardiol. 2011;Apr 19;57(16:1658–1665.

Singhal S, Ferraris VA, Bridges, CR, Clough ER, Mitchell JD, Fernando HC, Shrager JB. Management of Alveolar Air Leaks After Pulmonary Resection. Ann Thorac Surg. 2010:Apr; 89(4):1327–35.

Stanley GA, Arko FR 3rd, Foteh MI, Jessen ME, DiMaio JM. Hybrid endovascular treatment of an anomalous right subclavian artery dissection in a patient with Marfan syndrome. Ann Thorac Surg. 2012;Aug;94(2):639–41. Epub 2012 May 10.

Stanley GA, Arko FR 3rd. Endurant continues to impress, but long-term data are still needed for success. J Endovasc Ther. 2012; Feb;19(1):67–9.

Stanley GA, Murphy EH, Knowles M, Ilves M, Jessen ME, Dimaio JM, Modrall JG, Arko FR 3rdVolumetric analysis of type B aortic dissections treated with thoracic endovascular aortic repair. J Vasc Surg. 2011;Oct;54 (4):985–92; discussion 992. Epub 2011 Sep 13.

Stone GW, Witzenbichler B, Weisz G, Rinaldi MJ, Neumann FJ, Metzger CD, Henry TD, Cox DA, Duffy PL, Mazzaferri E, Gurbel PA, Xu K, Parise H, Kirtane AJ, Brodie BR, Mehran R, Stuckey TD. Platelet Reactivity and Clinical Outcomes in Patients Receiving Drug-eluting Stents. Lancet, (Vol. 382, Iss. 9892): 614–623. 17 August 2013.

Swain JD, Fargnoli AS, Katz MG, Tomasulo CE, Sumaroka M, Richardville KC, Koch WJ, Rabinowitz JE, Bridges CR.  MCARD-mediated gene transfer of GRK2 inhibitor in ovine model of acute myocardial infarction. J of Cardiovasc Transl Res. 2013 Apr; 6(2): 253–62.

Takach TJ, Kane PN, Madjarov JM, Hollerman JH, Nussbaum T, Robicsek F, Roush, TS. Acute Mesenteric Dissection. J Vasc Surg. May 2012.

Turner II, Turek JW, Jaggers JJ, Herlong JR, Lawson DS, Lodge AJ. Anomalous aortic origin of a coronary artery: Preoperative diagnosis and surgical planning. World J Pediatr Congenit Heart Surg. 2011; Jul1;2(3):340–345. 

Venermo MA, Arko FR 3rd, Salenius JP, Saarinen JP, Zvaigzne A, Zarins CK. EVAR may reduce the risk of aneurysm rupture despite persisting type Ia endoleaks. J Endovasc Ther. 2011;Oct;18(5):676–82. PMID: 21992639 

White JD, Thesier DM, Swain JD, Katz MG, Tomasulo C, Henderson A, Wang L, Yarnall C,  Fargnoli A, Sumaroka M, Isidro A, Petrov M, Holt D, Nolen-Walston R, Koch WJ,  Rabinowitz J, Stedman HH, Bridges CR. Myocardial Gene Delivery using Molecular Cardiac Surgery with Recombinant Adeno-associated Virus Vectors In vivo. Gene Ther. 2011;18:546–552.

Wright RS, Anderson JL Adams CD, Bridges CR, Casey DE, Ettinger SM, Fesmire FM, Ganiats TG, Jneid H, Lincoff  AM,  Peterson ED, Philippides GJ, Theroux P, Wenger NK, Zidar JP.  2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011;123(18): 2022–60.

Wright RS, Anderson JL Adams CD, Bridges CR, Casey DE, Ettinger SM, Fesmire FM,  Ganiats TG, Jneid H, Lincoff  AM,  Peterson ED, Philippides GJ, Theroux P, Wenger NK, Zidar JP.  2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2011;57: 1920–1959.

Wright RS, Anderson JF, Adams CD, Bridges, CR, Casey, DE Jr., Ettinger SM, Fesmire, FM, Ganiats, TG, Jneid H, Lincoff MA, Peterson, ED, Philippides, GJ, Theroux, P, Wenger, NK, Zidar, JP. 2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline); A Report of the American College of  Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Developed in collaboration with the American College of Emergency Physicians, Society for Cardiovascular Angiography and Interventions and Society of Thoracic Surgeons. J AM Coll Cardiol. 2011;57(19):e215–367.

Wright RS, Anderson JF, Adams CD, Bridges, CR, Casey, DE Jr., Ettinger SM, Fesmire, FM, Ganiats, TG, Jneid H, Lincoff MA, Peterson, ED, Philippides, GJ, Theroux, P, Wenger, NK, Zidar JP, Jacobs AK.  2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients WithUnstable Angina/Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline); A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice   Guidelines. Developed in collaboration with the American College of Emergency Physicians, Society for Cardiovascular Angiography and Interventions and Society of Thoracic Surgeons. Circulation 2011;123(18): 2022–60. 

National/International Presentations

Arko F. Evaluation of Two-Dimensional Aortic Arch Motion at the Origin of the Left Subclavian Artery: Importance of Respiratory Motion. AHA ATVB 2012. Chicago, IL. 

Arko F. Fenestration of the Left Subclavian Artery During Thoracic Endovascular Stenting is Safe, With Improved Outcomes Compared to Coverage and Left Subclavian Artery Bypass. Presented at: Peripherial Vascular Society Annual Meeting, 2012.

Arko F. Evaluation of Aortic Arch Motion in Physician-Modified Endografts During TEVAR. Prsented at Society of Vascular Surgeons. Washington, DC. 2012.

Arko F. A New Branched Graft for Left Subclavian Artery Revascularization During TEVAR. Presented at: China Heart Congress. Beijing, China, August 2012.

Browne, RE.  The Best Anticoagulation for Your Patients Now and In the Future.  Presented at: Cardiology Update for Primary Care Physicians Symposium. Charlotte, NC.  January 2012.

Downey, WE. The New Frontier: Using Catheters Instead of Surgery to Treat Structural Heart Disease.  Presented at: Cardiology Update for Primary Care Physicians Symposium. Charlotte, NC. January 2012.

Fandetti, GA. The Acute Coronary Syndrome Survival Guide: 10 Advances in Heart Attack Care.  Presented at: Cardiology Update for Primary Care Physicians Symposium.  Charlotte, NC. January 2012.

Frick S, Bray C, Scannell B, Jackson B, Roush TS, Brighton B. The Perfused Pulseless Supracondylar Humerus Fracture: Intermediate Followup of Vascular Status and Function. Presented at: Pediatric Orthopaedic Society of North America. May 2012.

Gulati S. Heart Success Transitional Care and Heart Failure Device Diagnostics Management.  Presented at: Cardiovascular Leadership Forum, Medtronic. Memphis, TN, October 2012.

Gulati S. Qualification of Intrathoracic Impedance with Heart Failure Functional Capacity and Biomarkers.  IMPEDE-HF Study. Presented at: HRS Scientific Sessions 2012. Boston, MA, August 2012.

Holshouser, JW.  Advances in Pacemakers and Implantable Defibrillators – What Every Primary Care Doctor Needs to Know. Presented at: Cardiology Update for Primary Care Physicians Symposium. Charlotte, NC. January 2012.

Johnson, TV.  When to Order Stress Tests and Echocardiograms. Presented at: Cardiology Update for Primary Care Physicians Symposium. Charlotte, NC. January 2012.

Levack MM, Jassar AS, Ryan LP, Jackson BM, Keane MG, St John-Sutton MG, Gorman JH, Gorman RC. Quantitative Three-Dimensional Analysis of Bicuspid Aortic Valves: A Single Modality Approach for Characterization of Valvular and Proximal Aortic Pathology. Presented at: 4th Annual Joint Scientific Session of the Heart Valve Society of America and Society for Heart Valve Disease. New York, NY. April 2012.

Levack MM, Eperjesi TJ, Weiss SJ, Gorman JH, Gorman RC, Ryan LP. Three-dimensional Echocardiography as a Predictive Instrument for Repairability of Regurgitant Bileaflet Aortic Valves. Presented at: AATS Aortic Symposium. San Francisco, CA. April 2012.

Levack MM, Jassar AS, Ryan LP, Jackson BM, Keane MG, St John-Sutton MG, Gorman JH, Gorman RC.  Quantitative Three-Dimensional Analysis of Bicuspid Aortic Valves: A single Modality Approach for Characterization of Valvular and Proximal Aortic Pathology.  Presented at: American College of Surgeons, Surgical Forum.  Chicago, IL. September 2012.

Madjarov, JM. Minimally Invasive Coronary Surgery. Presented at: St. Ekaterina Hospital, Sofia, Bulgaria, November 2011.

Marsden B, Nordin N, Arts J, Boyes C, Nels-Bogenschneider S, Roush TS.  Carotid Endarterectomy in Octogenarians – Short- and Long-term Outcomes in a Single Center Series. Presented at: Peripheral Vascular Surgery Society. January 2012.

Mehta, R.  The Rhythm is Going to Get You: Not All That Hurts is a Heart Attack.  Presented at: Alliance of Cardiovascular Professionals. June 2012.

Mehta, R, Koala RBilling and Coding Scenarios. Presented at: The Practical Electrophysiologist. Medtronic, Inc., San Francisco, CA, June 2012.

Navarro, F. Carotid Stenosis: A Practical Approach. Presented at: Cardiology Update for Primary Care Physicians Symposium. Charlotte, NC, January 2012.

Powell, BD. CRT Device A-V and V-V Optimization Cases.  Presented at: 16th Annual Understanding and Managing Pacemakers, ICDs and CRT for the Allied Professional.  Minneapolis, MN, September 2012. 

Powell, BD. Diagnosis and Management of Inappropriate ICD Shocks. Presented at: 16th Annual Understanding and Managing Pacemakers, ICDs and CRT for the Allied Professional. Minneapolis, MN, September 2012.

Powell, BD. Pacemaker and CRT Unknown Cases. Presented at: Electrophysiology Review for Boards and Recertification. Rochester, MN, September 2012.

Powell, BD. VT Workshop of Unknown Cases.  Presented at: Elecrophysiology Review for Boards and Recertification.  Rochester, MN, September 2012.

Rinaldi M. The Great Debates: Carotid Artery Stenting – No. Presented at: Controversies in Cardiovascular Disease Conference, Jeddah, Saudi Arabia, 2011.

Rinaldi M. The Great Debates: PFO: To Close or Not to Close? – No. Presented at: Controversies in Cardiovascular Disease Conference, Jeddah, Saudi Arabia, 2011.

Rinaldi MJ. The Great Debates: Percutaneous Treatment of Mitral Regurgitation – Yes. Presented at: Controversies in Cardiovascular Disease Conference, Jeddah, Saudi Arabia, 2011.

Rinaldi MJ. Early Adopter’s Experience with OCT and Image Interpretation. Presented at: St. Jude Fellows Course at ACC 2012, Chicago, IL, 2012.

Rinaldi MJ. Prevention, Detection, and Management of DVT and PE. Presented at: Watauga Medical Center Grand Rounds, Boone, NC, 2012.

Rinaldi MJ. Left Atrial Appendage Occlusion Devices for Stroke Risk Reduction. Presented at: NC/SC ACC Meeting, Charleston, SC, 2012

Rinaldi, MJ. Percutaneous Mitral Valve Therapy for Mitral Insufficiency. Presented at:  Grand Rounds, Greenville Memorial Hospital, Greenville, SC, 2011.

Rinaldi, MJ. Percutaneous Mitral Valve Therapy for Mitral Insufficiency. Presented at:  NC/SC ACC Meeting, Ashville, NC, 2011.

Rinaldi, MJ. Managing Iliac and Femoropopliteal Restenosis: Incidence, Diagnostic Tools, and Treatment Strategies. Presented at: TCT 2011, San Francisco, CA, 2011.

Rinaldi, MJ. The Great Debate: IVUS Is All You Need. Presented at: TCT 2011, San Francisco, CA, 2011.

Rinaldi, MJ. Degenerative Mitral Regurgitation Therapies: Case Presentation. Presented at: TCT 2011, San Francisco, CA, 2011.

Rinaldi, MJ. Building a Niche: How to Transition from the “New” Interventionalist to the Expert Group. Presented at: TCT 2011, San Francisco, CA, 2011.

Rinaldi, MJ. A Patient with Abdominal Pain, Anemia, and a Vascular Disorder. Presented at: TCT 2011, San Francisco, CA, 2011.

Rinaldi, MJ. Prevention, Detection, and Management of DVT and PE. Presented at: Watauga Medical Center Grand Rounds, Boone, NC, 2012.

Rinaldi, MJ. Left Atrial Appendage Occlusion Devices for Stroke Risk Reduction. Presented at: NC/SC ACC Meeting, Charleston, SC, 2012

Rinaldi, MJ. When Should the MitraClip be Considered for Front-Line Therapy of Degenerative MR? Presented at: TCT 2012, Miami, FL, 2012.

Rinaldi, MJ. Getting Started in an Academic Group Practice: What to Do and What Not to Do. Presented at: TCT 2012, Miami, FL, 2012.

Rinaldi, MJ. Platelet Response to DAPT and Clinical Outcomes - Lessons from Recent Clinical Trials. Presented at: BIT Conference 2012, Guangzhou, China

Rinaldi, MJ. Renal Nerve Denervation: A Promising Option for Refractory Hypertension. Presented at: SACS 2013, Amelia Island, FL 2013

Robicsek, F. Dinosaurs and Professors: Where Did They Go? Presented at: Southern Thoracic Surgical Association. San Antonio, TX. November 2011. 

Robiscek F, Padera RF, Thubrikar MJ. Dilation of the Ascending Aorta in Patients with Congenitally Bicuspid Aortic Valves. Presented at: Roland Hetzer International Cardiothoracic and Vascular Surgery Society. Freiburg, Germany. February 2012.

Robicsek F, Thubrikar MJ, Padera RF. Ascending Aortic Dilation in Patients with Congenitally Bicuspid Aortic Valves: The Answer. Presented at: American Association of Thoracic Surgery. New York, NY. April 2012.

Rose, GA. What is an ACO? Presented at: American Society of Echocardiography Scientific Sessions 2012. Washington DC.

Rose, GA. Best Practices Using Quality Standards to Reduce/Control Practice Costs. Presented at: American Society of Echocardiography Scientific Sessions 2012. Washington DC.

Rose, GA. Percutaneous Mitral Valve Repair. Presented at: NC/SC ACC Annual Meeting 2012. Charleston, SC. 

Rose, GA.  Case of the Year Winner. Presented at: South Atlantic Cardiovascular Society Annual Meeting 2012. Charleston, SC

Rose, GA. The Skinny on Fats – Insights from the New Guidelines for Lipid Management. Presented at: Cardiology Update for Primary Care Physicians Symposium.  Charlotte, NC. January 2012.

Ryan LP, Bavaria JE. TEVAR for Chronic Type B Aortic Dissection. Presented at: New York Society for Thoracic Surgery Annual Meeting. New York, NY. November 2011.

Stamou SC, Kouchoukos NT, Hagberg RC, Khabbaz K, Stiegel RM, Reames MK, Skipper E, Nussbaum M, Robicsek F, Lobdell KW. Does Operative Technique of Performing Distal Anastomosis in Acute Type-A Dissection Affect Early and Late Clinical Outcomes? Presented at: American Association for Thoracic Surgery. New York, NY. April 2012.

Symanski, JD. Heart Disease in Athletes – Screening Young Competitors and Weekend Warriors. Presented at: Cardiology Update for Primary Care Physicians Symposium. Charlotte, NC. January 2012.

Thomley, AM. Heart Failure Clinic – The Benefits of Specialized Care for a Common Problem. Presented at: Cardiology Update for Primary Care Physicians Symposium.  Charlotte, NC. January 2012.

Wilson, BH. Why Regionalization is important Lessons from Regional System Models Elements of the Ideal System Guideline Review of Reperfusion Strategy Data Solutions. Regional Systems of Care Demonstration Project: Mission: Lifeline – STEMI Systems Accelerator. Presented at: Tennessee Regional Systems of Care Demonstration Project Meeting 2012.

Wilson, BH. STEMI Systems of Care: The Race Experience. Presented at: Contemporary Cardiovascular Medicine Symposium at the Texas Heart Institute, Houston, TX 2012.

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