David A. Iannitti, MD

Chief, HepatoPancreaticoBiliary Surgery
Department of General Surgery
Clinical Associate Professor of Surgery, University of North Carolina School of Medicine

Prior Positions and Experience

2005 - 2006
Associate Professor of Surgery, Brown Medical School (Providence, R.I.)

1997 - 2005
Assistant Professor of Surgery, Brown Medical School

1995 - 1996
Assistant Clinical Instructor of Surgery, Brown Medical School

Education

MD: 1991, Brown University (Providence, R.I.)
BSc: 1987, Biology, Tufts University (Boston)

Research Interests

David Iannitti, MD,is the Chief of Hepatobiliary and Pancreatic (HBP) Surgery. In addition to clinical research in the area of surgical approaches to treat diseases of the digestive tract, he is engaged in basic research that focuses on the development and characterization of microwave ablation technology for the ablation of tumor masses. Dr. Iannitti also collaborates closely with Dr. McKillop in ongoing projects that address the fundamental pathophysiology of Hepatocellular carcinoma development and progression. Dr. Iannitti also oversees the HBP Fellows program at CMC including the research and clinical components.

Recent Publications

Hope WW, Vrochides DV, Newcomb WL, Mayo-Smith WW, Iannitti DA. Optimal treatment of hepatic abscess. Am Surg 2008; 74: 178-182. [PMID: 18306874]

Hope WW, Schmelzer TM, Newcomb WL, Heath JJ, Lincourt AE, Norton HJ, Heniford BT, Iannitti DA. Guidelines for power and time variables for microwave ablation in a porcine liver. J Gastrointest Surg 2008; 12: 463-467. [PMID: 17805939]

Iannitti DA, Martin RCG, Simon CJ, Hope WW, Newcomb WL, McMasters KM, Dupuy, D. Hepatic tumor ablation with clustered microwave antennae: The US Phase II Trial. HPB 2007; 9: 120-124. [PMID: 18333126]

Iannitti DA, Coburn NG, Somberg J, Ryder BA, Monchik J, Cioffi WG. Use of the round ligament of the liver to decrease pancreatic fistulas: a novel technique. J Am Coll Surg 2006; 203: 857-864. [PMID: 17116554]

Brunetti-Pierri N, Ng T, Iannitti DA, Palmer DJ, Beaudet AL, Finegold MJ, Carey KD, Cioffi WG, Ng P. Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates. Hum Gene Ther 2006; 17: 391-404. [PMID: 16610927]

Current, Recent and Pending Grant Support

Grant Title: A Phase I Trial of Hepatic Arterial Infusion of Oxaliplatin in Advanced Hepatocellular Carcinoma (BrUOG HC-100) (Providence, RI)
Role: Co-investigator
Years: 2004-Present

Grant Title: Hepatic Bipolar Radiofrequency Ablation in the Porcine Model (Providence, RI)
Funding Agency: Boston Scientific
Role: Principle Investigator
Years: 2004-Present

Grant Title: A Phase I Trial of Tarceva, Gemcitabine, Paclitaxel and Radiation for Locally Advanced Pancreas Cancer (BrUOG PA-94) (Providence, RI)
Role: Co-investigator
Years: 2003-2005

Grant Title: A Phase II Trial of PS341(Velcade) and Thalidomide for Hepatocellular Carcinoma (BrUOG HC-200) (Providence, RI)
Role: Co-investigator
Years: 2004-2005

Grant Title: Hepatic Microwave Ablation in Hepatic Malignancies. A Phase II Ablate and Follow Protocol
Funding Agency: Vivant/ValleyLab, Providence, RI
Role: Principal Investigator
Years: 2004-2005