Carolinas HealthCare System

Clinical Trial Phases

Clinical trials are often referred to in terms of phases. Here's what that means:

  • Phase I trials evaluate new (investigational) cancer drugs and drug combinations in patients with advanced cancer. A phase I trial usually enrolls only a small number of patients, sometimes as few as a dozen.

    In designing the new research and administrative headquarters for Levine Cancer Institute, a specialized Phase I unit is being planned. Although phase I investigation is already being conducted within the system, the development of this specialized unit will allow the Institute to greatly expand existing efforts and bring advances in the study and treatment of novel cancer therapeutics to patients more quickly.

    In an era where new treatments are being developed daily, the Phase I unit of the Institute will serve as a regional center of excellence for patients to receive exciting new therapies for the treatment of their cancers.

  • Phase II trials evaluate the feasibility and effectiveness of new treatments for specific cancers. Phase II studies usually focus on a particular type of cancer.

  • Phase III trials test new drugs, new drug combinations or new surgical procedures in comparison to current standards. A participant will usually be assigned to the standard group or the new group at random. Phase III trials often enroll large numbers of people and may be conducted at physicians' offices, clinics and cancer centers nationwide.

Source: National Cancer Institute

For more information about clinical trials at the Institute, contact a member of Levine Cancer Institute Oncology Research Management Team at 980-442-2000.

Learn more about Clinical Trials at Levine Cancer Institute

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