Research and Clinical Trials

Title  
Incyte INCB18424-271: A Single-Arm, Phase 2 Study of Ruxolitinib in Combination with Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease
Brief Description  
Primary: Assess the efficacy of ruxolitinib in combination with corticosteroids in subjects with Grade IIB-IVD acute graft-versus-host disease (GVHD). Secondary: Assess additional response and longer-term efficacy outcomes in the study population. Assess the incidence and severity of adverse events (AEs) and serious AEs. Evaluate the pK of ruxolitinib when administered in combination with corticosteroids. Exploratory: Incidence of secondary graft failure. Incidence of GVHD flares. Utilizatio
Who may be Eligible  
Please contact us for eligibility criteria.
Speciality/Disorder  
Other Hematopoietic
Status  
OPEN
Start Date  
04/04/2017
IRB Number  
00020270
Principal Investigator  
Grunwald, Michael Richard
Contact Name  
Asheton Asforis

For More Information, Contact  Asheton  , Asforis
Phone:  980-442-2345 Fax:    
Email:  Asheton.Asforis@carolinashealthcare.org
Address:1021 Morehead Medical Drive Suite 2200 Charlotte, 28204
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