Research and Clinical Trials

Title  
COG AREN0533: Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors
Brief Description  
This phase III trial is studying how well combination chemotherapy with or without radiation therapy works in treating young patients with newly diagnosed stage III or stage IV Wilms' tumor.
Who may be Eligible  

  • Newly diagnosed Wilms' tumor meeting 1 of the following criteria:
    • Stage IV disease with favorable histology
      • Has undergone nephrectomy within the past 2 weeks
    • Stage III disease with favorable histology transferring from clinical trial COG-AREN0532
      • Enrolled in this study before beginning week 7 chemotherapy
  • Previously enrolled in clinical trial COG-AREN03B2
  • Age up to 29 years
  • Not pregnant or nursing
  • No prior tumor-directed chemotherapy or radiotherapy unless transferring from clinical trial COG-AREN0532
  • No concurrent aprepitant
Speciality/Disorder  
Pediatric Cancer
IRB Number  
04-07-07B
Principal Investigator  
Kaplan, Joel

For More Information, Contact  Lynnae  , Schwandt
Phone:  (704) 355-1188  Fax:  (704) 446-1989  
Email:  lynnae.schwandt@carolinashealthcare.org
Address:1025 Morehead Medical Drive Suite 600 Charlotte, NC 28204
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