Hallervorden-Spatz disease is a movement disorder that is passed down through families (inherited).
Pantothenate kinase-associated neurodegeneration
Causes, incidence, and risk factors
Hallervorden-Spatz disease usually begins in childhood.
Most cases of Hallervorden-Spatz disease are due to a defect in a gene that makes a protein called pantothenate kinase 2. Patients with this genetic defect have a buildup of iron in parts of the brain.
Call your health care provider if your child develops:
Increased stiffness in the arms or legs
Increasing problems at school
Genetic counseling is appropriate in families affected by this illness. There is no known way to prevent it.
Lang A. Other movement disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 434.
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.