Carolinas HealthCare System

Research and Clinical Trials


Brief Description PrincipalĀ Investigator
To Evaluate Safety and Tolerability of Dalantercept Plus Axitinib in Patients with Advanced Renal Cell Carcinoma (RCC) to determine the recommended dose level of Dalantercept plus Axitinib for Part 2. Burgess, Earle Frederick 
To compare overall survival (OS) between study arms in subjects treated with AGS-003 in combination with standard treatment (combination arm) versus active control of standard treatment alone (control arm) Amin, Asim 
To determine if treatment with nivolumab combined with ipilimumab will improve Progression Free Survival (PFS), Overall Survival (OS), or both compared to sunitinib monotherapy in subjects with previously
untreated metastatic renal cell carcinoma (mRCC).
Amin, Asim 
The purpose of this study is to classify patients with renal tumors by histological categorization, surgicopathological stage, presence of metastases, age at diagnosis, tumor weight and loss of heterozygosity for chromosomes 1p and 16q, to thereby define eligibility for a series of therapeutic studies. Kaplan, Joel Adam 
The purpose of this registry is to collect information on patients who are receiving treatment with Proleukin in an organized way, and to learn more about patient care during and after treatment. Amin, Asim 
Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor. This phase III trial is studying everolimus to see how well it works in treating patients with kidney cancer who have undergone surgery. Amin, Asim 
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