The University of North Carolina (UNC) and Carolinas HealthCare System formally designated Carolinas Medical Center as the Charlotte Campus of the UNC School of Medicine in 2010.

Carolinas Medical Center (CMC) has played an active role in providing clinical education for third and fourth year UNC medical students for more than 40 years. Those students have completed rotations at CMC in a wide variety of medical specialties as part of their overall training.

The expansion of the UNC School of Medicine is intended to help combat the expected shortage of physicians in coming years. Expanding the medical school role of regional campuses is part of a strategy to not only increase the number of physicians overall, but to encourage graduates to practice in small towns and rural areas.