Carolinas HealthCare System
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Research

Summary of Research Mission
Our mission is to promote research that positively impacts the health of our community. We strive to accomplish this aim by reducing health disparities; enhancing access to primary care; and improving the quality of healthcare services. Research in our department is designed to be translational and rapidly disseminated into practice. We provide research opportunities for students and learners from a wide range of disciplines who are interested in primary care research or public health.
Contact Information
Research Interest: Community Health and Healthcare Disparities
Current, Recent and Pending Funding 
Grant Title: Provision of Group Prenatal Care for Charlotte's Underserved Communities
Funding Agency: SOPHIA grant
Role: Principal Investigator
Years: 2008-2009
Mary Hall, MD
Department Chair
Recent Publications
Davis CH 3rd, Hall MN, Kaufman L, Danis P. Clinical inquiries. What is the best way to evaluate secondary infertility? J Fam Pract 2007; 56: 573-575. [PMID: 17605951]
Hall MN, Leach L, Kynerd R. Clinical inquiries. In menopausal women, does fatigue indicate disease? J Fam Pract 2005; 54: 895-896.[PMID: 16202379]
Hall MN, Leach L, Beck E. Clinical inquiries. Which blood tests are most helpful in evaluating pelvic inflammatory disease? J Fam Pract 2004; 53: 326,330-331.[PMID: 15068781]
 
Sindy McCrystle, ANP-C, MSN 
Recent Publications
McCrystle S, Menscer D. Managing the patient with dementia in primary care. N. C. Med J 2005; 66: 53-56.[PMID: 15786680]
Current, Recent and Pending Grant Support
Grant Title: Healthy Brain Project
Funding Agency: Carolinas Geriatric Education Grant (CGEC)
Role: Principal Investigator
Years: 2008-2011
 
Vanessa McPherson, MD
Residency Director
Recent Publications 
Kaiser J, McPherson V, Kaufman L, Huber T. Clinical inquiries. Which UTI therapies are safe and effective during breastfeeding? J Fam Pract 2007; 56: 225-228. [PMID: 17343814]
McPherson V, Wright ST, Bell AD. Clinical inquiries. What is the best treatment for gastroesophageal reflux and vomiting in infants? J Fam Pract 2005; 54: 372-375. [PMID: 15833233]
McPherson V, Leach L, Erlanger L. Clinical inquiries. What is the best treatment for analgesic rebound headaches? J Fam Pract 2005; 54: 277-278. [PMID: 15755384]
 
Recent Publications
McCrystle S, Menscer D. Managing the patient with dementia in primary care. N C Med J 2005; 66: 53-56.[PMID: 15786680]
 
David Price, MD
Associate Director, Family Medicine Fellowship in Primary Care Sports Medicine

Research Interests
Concussion impact research using helmet G force sensors
Patient knowledge of family medicine
Sports screening research
Director: Heart of a Champions Day
Recent Publications
Price D, Betancourt V, Kaufman L, Rodríguez JE. FPIN's clinical inquiries. Treatment of impetigo. Am Fam Physician 2007; 75: 703-704.[PMID: 17375518]
Price DE, Elder K, White RD. "Exercise Testing."  In O'Connor, Wilder, Sallis and St. Pierre (eds.).  Sports Medicine-Just the Facts.  McGraw-Hill. 2005; 118-126.
Price DE, Elder K, White RD: Exercise Stress Testing. In O'Connor, Sallis Wilder, and St. Pierre (eds.).  Sports Medicine-Examination & Board Review.  McGraw-Hill. 2005:  25-26.
 
Lawrence Raymond, MD, ScM
704-446-7708
704-446-7795 Fax
Research Interests
Testing ways of adding heat stress to exertional stress of treadmill electrocardiography, for medical evaluation of candidates for work with hazardous materials (Hazmat Duty)
Effects of collaborative practice with onsite Nurse Practitioners on employer healthcare costs and other outcomes
Effects of tissue oxygenation and related factors on extremity wounds in persons with diabetes mellitus
Health aspects of homeland security worker

Dr. Raymond plans to initiate an observational study of the natural history of transcutaneous oxygen measurements in older persons with diabetes during the next year, and compete the first phase of such a study over the next five years. The current study of treadmill heat stress testing will be completed and submitted for publication by end-2008, while observational work with onsite Nurse Practitioners will continue in 2008-2013.
Dr. Raymond completed a fellowship in pulmonary medicine in the laboratory of Dr. John Severinghaus, Cardiovascular Research Institute, University of California, San Francisco.
Recent Publications
Raymond LW, Pankowski J, Shiflett H, Hall D. Caring for the wood-workers: Two-year outcomes of a lumberyard wellness incentive program. J Investig Med 2013;61:130  
Raymond LW, Pankowski J, Yanni A, Hall D. Biometric monitoring in foundry and plastic pipe workers: 2010-2011 results in an incentive-driven program. J Investig Med 2013;61:183-184 (Abstract 256)
Raymond LW, Carr J, Only C, Yeomans J, Salmon JS. Abiraterone-associated delirium: Recurrence with retreatment. J Investig Med 2013;61:131 (Abstract 69).
Raymond LW. Conglomerate pulmonary fibrosis: Mica, silica, both or neither? 15-year follow-up. J Investig Med 2013;61:213 (Abstract 359).
Knost S, Marroum MC, Nozar T, Tagle L, Horton J, Raymond LW, Kase J, Kilpatrick S, Beohringer W, Peng AY, Sautter RL. Sniff the plates? Laboratory exposure to Burkholderia pseudomallei. Clin Microbiol Newsletter 2013;35:31-33.
Davis L, Urbina I, Raymond LW, Wofford B. A toxic trade. New York Times,  March 31, 2013.  http://www.nytimes.com/video/2013/03/30/us/100000002126767/a-dangerous-trade.html
Raymond LW, Jones MM, Warren E, Weinrib DA. Inguinal phlegmon and positive serology for syphilis after penile bite laceration: true, true and unrelated. Am J Emerg Med 2008; 26: 250.e7-8 [PMID: 18272128]
 
Research Interests: Prevention and Healthy Lifestyle Interventions in the Community
Dr. Saxe received her medical degree from Tufts University School of Medicine and was trained in Duke University Family Medicine program. Dr. Saxe has submitted a grant application for a healthy lifestyle intervention in a low-income community based on a successful small pilot. She would like to bring healthy lifestyle interventions to more communities.
Current, Recent and Pending Grant Support
Grant Title: School Healthlink at Bruns Elementary School
Funding Agency: Kate B. Reynolds Foundation
Role: Principal Investigator
Years: 2003 - 2007
 
Research Interests: Integration of Complementary and Alternative Medicine into Primary Care Faculty Development
Current Studies
Effect of Web-Based Educational Intervention on botanical Medicine on the Knowledge Base and Practice Pattern of Primary Care Residents
Recent Publications
Lebensohn P, Dodds S, Benn R, Brooks A, Birch M, Cook P, Schneider C, Sroka S, Waxman D, Maizes V.  Resident Wellness Behaviors: Relationship to Stress, Depression and Burnout. Family Medicine (Accepted for publication).
Alexander M, Waxman D, White P. What's eating Gilbert Grape: a case study of chronic illness. Journal for Learning through the Arts 2007; 2.[Article]
Waxman D, et al, "Chapter 5: Family Dynamics", "Chapter 11: Anxiety, Depression, and Somatoform Disorders", and "Chapter 17: Interviewing Skills" in Cinemeducation: A Comprehensive Guide to Using Film in Medical Education.  Alexander M, Lenahan P, and Pavlov A, Editors. Oxford, Radcliffe Publishing. 2005.
Other Presentations
“Collaborative Care in a Primary Care Practice.”  Introduction to Integrative Pastoral Care Course, Carolinas College of Health Sciences, Feb. 22, 2013.  (Invited)
“Mindfulness”,  Integrative Oncology Symposium, Levine Cancer Institute, Carolinas Medical Center. February 8,  2013 (invited speaker)
“Wellness Journeys”,  LiveWell Carolinas/Human Resources Retreat, Lunchtime Speaker (invited), January 28, 2013
Recent Publications
Alexander M, Waxman D, White P. What's eating Gilbert Grape: a case study of chronic illness. Journal for Learning through the Arts 2007; 2. [Article]
 
Irene Zink, MD

Research Interests: Community Health and Resident Education
Hazel Tapp, Research Office: 704-304-7120 / 704-304-7102 Fax
Department of Family Medicine: 704-304-7110
Mailing address:
Department of Family Medicine 
2001 Vail St.
Charlotte, NC 28207
Faculty Research Interests
 
 
 
 
 
 
 
 
 
Michael Dulin, MD, PhD
Research Director
704-446-7740

Dr. Dulin's research interests center on improving access to and the quality of primary care services. He currently serves as the Research Director for the Department of Family Medicine and Directs the Mecklenburg Area Partnership for Primary Care Research (MAPPR).
Dr. Dulin was awarded a PhD in neurophysiology prior to receiving his MD at The University of Texas at Houston Medical School. He completed residency training in Family Medicine at CMC and then worked in private practice in Dr. Dullin's Research TeamHarrisburg for three years. In 2004, he returned to academia by joining the CMC Department of Family Medicine as the director of research and evidence-based medicine. He completed additional fellowship training at UNC-Chapel Hill School of Medicine and recently completed the AAFP's national Grant Generating Project.
While at CMC, he founded the Mecklenburg Area Partnership for Primary Care Research (MAPPR) in collaboration with UNC-Charlotte, the local and state Health Departments, and the Latin American Coalition. Dr. Dulin is also co-founder of a statewide consortium of research networks, the North Carolina Network Consortium (NCNC), which includes networks from UNC-Chapel Hill, Duke University and East Carolina University. Dr. Dulin was selected by the Robert Wood Johnson Foundation to the 2008 class of their Physician Faculty Scholars Program that will assist him with funding for his research endeavors and additional training for the next three years.
The Mecklenburg Area Partnership for Primary Care Research (MAPPR)
The Mecklenburg Area Partnership for Primary Care Research is a practice-based research network (PBRN) designed to study barriers to healthcare access for the growing Latino population in Charlotte. The goal for this network is to utilize different sectors of the community to bring about positive change in individual's lives by improving healthcare and quality of life.
The network comprises ambulatory care clinics located within Carolinas HealthCare System (such as Eastland Family Practice, CMC-NorthPark and CMC-Myers Park Pediatrics), private/otherwise affiliated practices and community advocacy organizations (such as the Latin American Coalition, El Centro Betesda and Our Lady of Guadalupe church).
MAPPR is headquartered at the Department of Family Medicine, under the leadership of Michael Dulin, MD, PhD, and is funded through the Agency for Healthcare Research and Quality.

Recent Publications
Tapp H and Dulin MF. The Science of Primary Healthcare Improvement: Potential and Use of Community Based Participatory Research by Practice Based Research Networks for Translation of Research into Practice. 2010. Experimental Biology and Medicine. In Press.

Dulin MF, Ludden T, Blackwell J, Tapp H, Hernandez B, Furuseth O, Smith HA. (2010) Using Geographical Information Systems to Understand a Community's Primary Care Needs, JABFM 23(1):13-21.
Dulin MF, Ludden T, Blackwell J, Tapp H, Hernandez B, Furuseth O, Smith HA. (2009) Application of MAPCATS to Target Interventions to Improve Healthcare Access for a Transitioning Hispanic Community, JABFM 23(1): 109-120.
Pearson WF, Dube SR, Seeff LC, Ford ES, Mokdad AH and Dulin MF (2009) A Population Based Study Examining Language as a Predictor of Colorectal Cancer Screening Among Overweight and Obese Hispanic Adults in the United States. Open Epi. Journal 2:44-50.
Hirsch MA, Dulin MF, Iyer SS, and Hammond FM. (2009)  Exercise for Management and Treatment of Parkinson Disease, American Family Physician, 79(12) 1043.
Dulin MF, Kennard T, Leach L. (2008) Cervical Adenitis. FPIN, American Family Physician, 78(9) 1079.
Dulin MF, Hatcher LA, Sasser HC, and Barringer TA (2006).  Policosanol Ineffective in Treatment of Hypercholesterolemia: A Randomized Controlled Trial. Am. J. Clin. Nutr. 2006 Dec;84(6):1543-8.
Gasull X, Liao X, Dulin MF, Phelps C, and Walters ET (2005).  Evidence that long-term hyperexcitability of the sensory Neuron soma induced by nerve injury in Aplysia is adaptive. J. Neurophysiol. 94(3):2218-30.
Walters ET, Bodnarova M, Billy A, Dulin MF, and Moroz, LL (2004) Somatotopic organization and functional properties or mechanosensory neurons expressing Sensorin-A mRNA in Aplysia californica.  J. Comp. Neurol. 471(2):219-40
Current, Recent and Pending Grant Support
Grant Title: Community Participatory Approach to Improving the Health of a Hispanic Population (#R24 MD004930-01)
Funding Agency: NIH / NCMHD
Role: Principal Investigator
Years: 2009-2011
Grant Title: Primary Care Practice Based Research Networks (PBRNs)
Funding Agency: Agency for Healthcare Research and Quality  (RFP #AHRQ-06-0029)
Role: Co-Investigator
Years: 2007-2012
Grant Title: A Community-Based Participatory Approach for Improving Primary Care Access
Funding Agency: The Robert Wood Johnson Foundation
Role: Principal Investigator
Years: 2008-2011
Grant Title: Development of Geospatial Models to Evaluate Interventions Designed to Enhance Primary Care Access for Vulnerable Populations, (#2KR10806)
Funding Agency: NC TraCS Institute
Role: Principal Investigator
Years: 2009-2010
Grant Title: Disease Management and Health Promotion in the Ambulatory Care Setting
Funding Agency: The Duke Endowment
Role: Principal Investigator
Years: 2007-2011
Grant Title: Action to Control Cardiovascular Risk in Diabetes (ACCORD) 
Funding Agency: NHLBI / NIH
Role: Local Co-Investigator
Years: 2001-2009
Grant Title: Creation of a PBRN to Study Healthcare Delivery to a Transitioning Community
Funding Agency: Agency for Healthcare Research and Quality  (R03 HS016023-01)
Role: Principal Investigator
Years: 2006-2008
 
Hazel Tapp, PhD
Tapp H and Dulin MF. The Science of Primary Healthcare Improvement: Potential and Use of Community Based Participatory Research by Practice Based Research Networks for Translation of Research into Practice. 2010. Experimental Biology and Medicine. In Press.
Dulin MF, Ludden TM, Tapp H, Smith HA, de Hernandez BU, Blackwell J, Furuseth OJ. Geographic Information Systems (GIS) demonstrating primary care needs for a transitioning hispanic community. J Am Board Fam Med. 2010 Jan-Feb;23(1):109-20. PMID: 20051550 [PubMed - in process]
Dulin MF, Ludden TM, Tapp H, Blackwell J, de Hernandez BU, Smith HA, Furuseth OJ. Using Geographic Information Systems (GIS) to understand a community's primary care needs. J Am Board Fam Med. 2010 Jan-Feb;23(1):13-21. PMID: 20051538 [PubMed - in process]
Tapp H, Smith HA, Dixon JT, Ludden T, Dulin M. Evaluating Primary Care Delivery Systems for an Uninsured Hispanic Immigrant Population. Family and Community Health. 2013 Jan;36(1):19-33.
Tapp H, Deepe R, Ingram JA, Kuremsky M, Hanley EN Jr., and. Gruber HE. Adipose-derived Mesenchymal Stem Cells from the Sand Rat:  TGFß and 3D Coculture with Human Disc Cells Stimulate Proteoglycan and Collagen Type I Rich Extracellular Matrix. Arthritis Research and Therapy  2008 10:R89.
Tapp H, Hanley EN Jr, Patt JC, Gruber HE  Adipose-Derived Stem Cells: Characterization and Current Application in Orthopaedic Tissue Repair. Experimental Biology and Medicine. Exp Biol Med (Maywood). 2009 Jan;234(1):1-9.
Tapp H, Deepe R, Ingram J, Yarmola E, Hanley E Jr, Gruber H. Exogenous thymosin beta(4) prevents apoptosis in human intervertebral annulus cells in vitro. Biotech Histochem. 2009 Jul 25:1-8.
Tapp H, Al-Naggar IM, Yarmola EG, Harrison A, Shaw G, Edison AS, Bubb MR.  MARCKS is a natively unfolded protein with an inaccessible actin-binding site: Evidence for long-range intramolecular interactions. J. Biol. Chem   2005 280 9946-9956.
Current, Pending and Recent Research Support
Grant Title: "Efficiency of Primary Care Delivery to Uninsured Hispanics in Charlotte NC. UNC Charlotte and CMC joint grant initiative."
Funding Agency: UNCC/CMC
Role: Joint PI
Years: 1/1/09-1/1/10.
Grant Title: "Community Based Approach to Improving Health in a Hispanic Population. Funding Agendcy: NIH/NCMHD (RFA-MD-09-006).
Role: Investigator
Years: 10/2009-10/2011
Grant Title: Disease Management and Health Promotion in the Ambulatory Care Setting
Funding Agency: The Duke Endowment
Role: Investigator
Years: 2007-2011
 
 
Research Interests: Qualitative Research; Educational Innovations; Spirituality in Medicine; Behavioral Medicine
Recent Publications
Alexander M. A psychologist collaborating with an inpatient family medicine team. Annals of Behavioral Science and Medical Education 2008; in press. 
Alexander M, Waxman D, White P. What's eating Gilbert Grape: a case study of chronic illness. Journal for Learning through the Arts 2007; 2. [Article]
Alexander M. Finding meaning in serious illness: the hows and whys of the spiritual meaning interview. Annals of Behavioral Science and Medical Education 2006; 12. 
Michele Birch, MD
Other presentations
Birch M. “Role of Diet in Cancer Prevention and Treatment.” Integrative Oncology Symposium, Levine Cancer Institute, Carolinas Medical Center. February 2013 (Invited speaker)
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