The Depatment of Family Medicine clinical trials team consists of highly trained research staff, coordinators, and clinical nurses who direct studies that are of direct benefit to the patient population we serve. Our clinical trials site is co-located within a busy primary care clinic, Elizabeth Family Medicine, which helps facilitate patient access, recruitment, and seamless communication with our practicing physicians.

We currently do not have any trials actively enrolling patients. Check back soon for new information on trials for patients with diabetes and early memory impairment.

Current Clinical Trials

Accordion

1/1/2011 - 1/1/2015 | A prospective, observational follow-up study of at least 8,000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial. Treatment in ACCORD ended in 2009 and ACCORDION is designed to further elucidate the long-term effects of the ACCORD treatment strategies and provide additional data on the relationships among various cardiovascular and diabetic risk factors.

CURRENT STATUS: Enrolled subjects in follow up status Use this home page to get an overall sense of the project. Use the links located under Team Links to the left to view all documents and items pertaining to Budgets, Patient Information, Project Documents, Calendar Events and Tasks.

TECOS

1/1/2010 - 1/1/2017 | Trial Evaluating Cardiovascular Outcomes with Sitagliptin: TECOS is designed to assess cardiovascular outcomes of long-term treatment with sitagliptin. This clinical trial is in collaboration with Duke Clinical Research Institute and Oxford University. It is an international trial being conducted in 23 countries with a projected 14, 000 patients worldwide.

CURRENT STATUS: Subjects in treatment Use this home page to get an overall sense of the project. Use the links located under Team Links to the left to view all documents and items pertaining to Budgets, Patient Information, Project Documents, Calendar Events and Tasks.

Dementia

"A Pilot to Investigate the Operational Feasibility and Testing Effectiveness of Telephonic Administration of Scales for the Assessment of Possible Cognitive Impairment in Primary Care Practice Settings"

5/1/2013 - 10/31/2013 | AstraZeneca is interested in testing the feasibility of utilizing centralized, telephone-based testing to identify patients with early cognitive or memory deficits. This initial study aims simply to see if we can identify and perform neurocognitive testing on a cohort of patients with a memory/cognitive complaint. This cohort and similar patients may be candidates for a future study testing a new biologic therapy to treat very early Alzheimer’s disease. The neurocognitive testing includes the AD8 and Rey AVLT, which will be administered by trained clinicians at a company called MedAvante. Both of these tests have performed well in studies examining validity and discriminative properties to differentiate those patients who have dementia and those who do not.

SPRINT

9/1/2009 - 9/1/2018 | Systolic Blood Pressure Intervention Trial (SPRINT): Is a 2-arm multicenter, randomized clinical trial designed to test whether a treatment program aimed at reducing systolic blood pressure to a lower goal than currently recommended will reduce cardiovascular risk, kidney disease, stroke, and age-related declines in memory and thinking.

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