Research Technician II
Liver & Digestive Diseases Laboratory & Molecular Biology Core Facility
Cannon Research Center
Carolinas Medical Center
Prior Positions and Experience
||Research Assistant, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden
||Research Assistant, Department of Virology, Swedish Institute for Infectious Diseases Control, Stockholm, Sweden
||Research Technician, Research Center for Gastroenterology, and Liver Diseases, Tehran, Iran
MS in Molecular Cell Biology; 2006-2007 Uppsala University, Sweden
BS in Applied Chemistry; 1995-2000 Tehran Azad University, Tehran, Iran
Marjan Mohseni has been working in the field of viral hepatitis for seven years. She joined in the Liver Group of the Research Center for Gastroenterology and Liver Diseases in Tehran, Iran, in 2002 working under the supervision of Professor Mohammad R. Zali. While in this lab, she worked on the molecular epidemiology of viral hepatitis.
Her collaboration with the Swedish Institute for Infectious Diseases Control led to Marjan and her husband joining the group to carry on their research under the supervision of Professor Lars Magnius in late 2003.Marjan examined the molecular epidemiology of hepatitis B and their efforts led to the identification of a novel core promoter mutation in HBV isolates of Hepatitis B patients that was published in journal of General Virology. Marjan also worked on the molecular epidemiology of viral hepatitis A, C, and E while in Sweden as well as the complete genome sequencing of enterovirus strains in a European multi-country project called Vizier.
Marjan's master thesis project involved the epigenetic reprogramming of host by CMV. She assisted in a collaborative project under supervision of Professor Tomas Ekstrom to identify DNMT1 translocation out of the cell by CMV transfection.
Currently, Marjan is working in Liver, Biliary and Pancreatic lab under the supervision of Professor Herbert Bonkovsky, MD,examining the effect of Silymarin on HCV replication. She is also collaborating in a project which studies molecular pathogenesis of HCV by micro RNA. Additionally, she is also working in molecular biology core facility at Cannon Research Center under the supervision of Dr. Nury Steuerwald.
Sendi H, Mehrab-Mohseni M, Shahraz S, Norder H, Alavian SM , Noorinaye B, Zali MR, Pumpens P, Bonkovsky HL, Magnius LO. CTL escape mutations of core protein are more frequent in strains of HBeAg negative patients with low viral load. J Clin Virol 2009; 46:259-264. PMID: 19748824
Sendi H, Mehrab-Mohseni M, Zali MR, Norder H, Magnius LO. T1764G1766 core promoter double mutants are restricted to Hepatitis B virus strains with an A1757 and are common in genotype D. J Gen Virol 2005; 86: 2451-8. [PMID: 16099903]