The Electron Microscopy Facility has trained, certified technicians for transmission electron microscopy. Its mission is to provide ultrastructural support for studies developing translational links between research and patient care, and to assist pathologists in processing, sectioning and documentation of biopsies and other clinical specimens. The laboratory is directed by Helen Gruber, PhD. Daisy Ridings, BS, is a certified electron microscopy technician who is the laboratory supervisor. Patsy (Pat) McCoy, BS, and David Radoff,MS, offer expert technical support in the laboratory.
The laboratory has a Phillips CM10 transmission electron microscope with a digital imaging system, two ultramicrotomes, complete darkroom facilities, and a separate workstation for digital imaging requirements.
Helen Gruber, PhD, Director
Daisy Ridings, BS, Lab Supervisor
Pat McCoy, BS, Research Tech II
David Radoff, MS, Research Tech II
Khristina Bretthauer, Staff Assistant
Publications Resulting from Collaborations with Other Laboratories
Singer FR, Mills BG, Gruber E, Windle JJ, Roodman GD. Ultrastructure of bone cells in Paget's disease of bone. J Bone Miner Res 2006; 21: P51-P54. [PMID: 17229009]
Bosse MJ, Gruber HE, Ramp WK. Internalization of bacteria by osteoblasts in a patient with recurrent, long-term osteomyelitis. A Case Report. Journal of Bone and Joint Surgery 2005; 87A: 1343-1347. [PMID: 15930546]
Gruber HE and Hanley EN Jr. Ultrastructure of inclusion bodies in annulus cells in the degenerating human intervertebral disc. Biotechnic & Histochemistry. 84(3):85-94, 2009 [PMID: 19370472]