Carolinas HealthCare System

Transfusion Services

Transfusion Services performs more than 42,000 tests per year for transfused blood products. These safe and effective blood transfusions are for inputs and outputs including trauma, transplant, neonatal, cancer and sickle cell patients. In addition to transfusion testing, the blood bank also performs prenatal, cord blood and organ donor testing. The AABB and CAP accredited blood bank also serves as a reference laboratory for antibody testing. Crossmatches and specific antibody identifications are performed by highly trained medical technologists. This lab area also has the ability to investigate and resolve the following immunohematology concerns:

  • single and complex multiple antibodies
  • autoantibodies
  • hemolytic disease of the newborn
  • hemolytic transfusion reaction
  • antibodies to high and low incidence antigens
  • aberrant and/or discrepant red cell antigens
  • typing results, including ABO
  • subgroups and other weak antigen expressions
  • reagent-dependent reactivity
  • polyagglutination

Two instruments that aid in specimen testing are the Rosys and the ABS2000. The Rosys performs routine prenatal and pre-surgical blood typing as well as antibody screens. With a capacity of testing 96 samples at once, the instrument also performs blood type confirmation testing and antigen typing. The ABS2000 performs routine and STAT blood types plus antibody screens. Both instruments use solid phase technology which is thought to be the most sensitive technology available for detecting antibodies.

Most of the blood transfused in Carolinas HealthCare System is from the Community Blood Center of the Carolinas, a locally established blood collection facility that provides red cells, platelets, fresh frozen plasma, cryopoor plasma and cryoprecipitate.

For additional information concerning transfusion therapies please visit

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