Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase.
Author(s): Powell NA, Hoffman JK, Ciske FL, Kaufman MD, Kohrt JT, Quin J, Sheehan DJ, Delaney A, Baxi SM, Catana C, McConnell P, Ohren J, Perrin LA, Edmunds JJ
Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036.
Author(s): Chan WW, Wise SC, Kaufman MD, Ahn YM, Ensinger CL, Haack T, Hood MM, Jones J, Lord JW, Lu WP, Miller D, Patt WC, Smith BD, Petillo PA, Rutkoski TJ, Telikepalli H, Vogeti L, Yao T, Chun L, Clark R, Evangelista P, Gavrilescu LC, Lazarides K, Zaleskas VM, Stewart LJ, Van Etten RA, Flynn DL
Course of relapsing-remitting multiple sclerosis before, during and after natalizumab.
Author(s): Kaufman MD, Lee R, Norton HJ
A phase 3 trial of extended release oral dalfampridine in multiple sclerosis.
Author(s): Goodman AD, Brown TR, Edwards KR, Krupp LB, Schapiro RT, Cohen R, Marinucci LN, Blight AR, MSF204 Investigators
Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region.
Author(s): Ahn YM, Clare M, Ensinger CL, Hood MM, Lord JW, Lu WP, Miller DF, Patt WC, Smith BD, Vogeti L, Kaufman MD, Petillo PA, Wise SC, Abendroth J, Chun L, Clark R, Feese M, Kim H, Stewart L, Flynn DL
- Cerebral Aneurysm
- Cerebral Arteriogram
- Bell's Palsy
- Brain Abscess
- Cerebral Palsy
- Chiari Malformation
- Neurological Congenital Disorders
- Neurological Disorders
- Duchenne Muscular Dystrophy
- Electromyography (EMG/NCS)
- Evoked Potential Studies
- Head Injury
- Intraventricular Hemorrhage
- Lou Gehrig's Disease (ALS)
- Lumbar Puncture
Dr. Kaufman is President of the CMSC. He is also the past and inaugural Chairman of the Congressionally Directed MS Research Program.NMSS Volunteer Hall of Fame Inductee (2006)Best Doctors in America (2009)
- Multiple Sclerosis
- Muscular Dystrophy
- Myasthenia Gravis
- Nerve Conduction Velocity (NCV)
- Neurocutaneous Syndromes
- Neuromuscular Disease
- Neuromuscular Disorders
- Oculoplethysmography (OPG)
- Parkinson's Disease
- Periventricular Leukomalacia
- Reye's Syndrome
- Spina Bifida
- Spinal Muscular Atrophy (SMA's)
- Spinal Tap
- Brain Tumor