As a general rule, your doctor should examine any skin rashes, including vesicles.
Over-the-counter treatments are available for certain conditions that cause vesicles, including poison ivy and cold sores.
Call your health care provider if
Call your doctor if you have any unexplained blisters on your skin.
What to expect at your health care provider's office
Your doctor will look at your skin. Some vesicules can be diagnosed simply by how they look.
In many cases, however, additional tests are needed. The fluid inside a blister may be sent to a lab for closer examination. In particularly difficult cases, a skin biopsy may be needed to make or confirm a diagnosis.
Armstrong CA. Examination of the skin and approach to diagnosing skin diseases. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 462.
Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.