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Possible Interactions with: Passionflower

Also listed as: Passiflora incarnata; Passionflower

Interactions

Passionflower may interact with the following medications:

Sedatives (drugs that cause sleepiness) -- Because of its calming effect, passionflower may increase the effects of sedative medications. These can include:

  • Anticonvulsants such as phenytoin (Dilantin)
  • Barbiturates
  • Benzodiazepines such as alprazolam (Xanax) and diazepam (Valium)
  • Drugs for insomnia, such as zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Lunesta), ramelteon (Rozerem)
  • Tricyclic antidepressants, such as amitriptyline (Elavil), amoxapine, doxepin (Sinequan), and nortriptyline (Pamelor)

Antiplatelets and anticoagulants (blood thinners) -- Passionflower may increase the amount of time blood needs to clot, so it could make the effects of blood-thinning medications stronger and increase your risk of bleeding. Blood-thinning drugs include:

  • Clopidogrel (Plavix)
  • Warfarin (Coumadin)

Monoamine oxidase inhibitors (MAO inhibitors or MAOIs) -- MAO inhibitors are an older class of antidepressants that are not often prescribed now. Theoretically, passionflower might increase the effects of MAO inhibitors, as well as their side effects, which can be dangerous. These drugs include:

  • Isocarboxazid (Marplan)
  • Phenelzine (Nardil)
  • Tranylcypromine (Parnate)

Review Date: 4/25/2007
Reviewed By: Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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