You are pregnant, plan to become pregnant, or are breastfeeding.
Take this medicine with food and plenty of water to lower side effects. You may need to stop taking clopidogrel before you have surgery or dental work. Do NOT just stop taking your medicine without talking with your doctor or nurse first.
Talk with your doctor before taking any of these drugs:
Heparin and other blood thinners, such as warfarin (Coumadin)
Pain or arthritis medicine (such as diclofenac, etodolac, ibuprofen, indomethacin, Advil, Aleve, Daypro, Dolobid, Feldene, Indocin, Motrin, Orudis, Relafen, or Voltaren)
Phenytoin (Dilantin), tamoxifen (Nolvadex), tolbutamide (Orinase), or torasemide (Demadex)
Do not take other drugs that may have aspirin or ibuprofen in them. Read the labels on cold and flu medicines. Ask your doctor what other medicines are safe for you to take for aches and pains, colds, or the flu.
Tell your doctor if you are pregnant or planning to become pregnant, or breastfeeding or planning to breastfeed. Women in the later stages of pregnancy should not take clopidogrel. Clopidogrel can also be passed to infants through breast milk.
If you miss a dose:
Take it as soon as possible, unless it is time for your next dose.
If it is time for your next dose, take your usual amount.
Do NOT take extra pills to make up for a dose you have missed.
Store these drugs and all other medicines in a cool, dry place. Keep them where children cannot get to them.
When to Call the Doctor
Call your doctor if you have any of these side effects and they do not go away:
Any signs of unusual bleeding, such as blood in the urine or stools, nosebleeds, any unusual bruising, heavy bleeding from cuts, black tarry stools, coughing up blood, heavier than usual menstrual bleeding or unexpected vaginal bleeding, vomit that looks like coffee grounds
Tightness in your chest or chest pain
Swelling in your face or hands
Itching, hives, or tingling in your face or hands
Wheezing or difficulty breathing
Very bad stomach pain
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Kushner FG, Hand M, Smith SC Jr, King SB 3rd, Anderson JL, Antman EM, et al. 2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (updating the 2005 Guideline and 2007 Focused Update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2009 Dec 1;120(22):2271-306.
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Michael A. Chen, MD, PhD, Assistant Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.