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Creatinine - urine

Definition

Creatinine is a breakdown product of creatine, which is an important part of muscle. Creatinine is removed from the body entirely by the kidneys. This article discusses the test done to measure the amount of creatinine in your urine.

A blood test can also be used to determine your creatinine level. See: Serum creatinine

Alternative Names

Urine creatinine test

How the test is performed

A random urine sample or a 24-hour collection may used. For information on how to collect a 24-hour urine sample, see: 24-hour urine collection.

How to prepare for the test

Your health care provider may tell you to temporarily stop taking certain medicines that may interfere with test results. Such medicines include:

  • Cephalosporins (cefoxitin)
  • Cimetidine
  • Cisplatin
  • Gentamicin
  • Trimethoprim

How the test will feel

The test involves only normal urination, and there is no discomfort.

Why the test is performed

This test can be used as a screening test to evaluate kidney function. It may also be used as part of the creatinine clearance test. It is often used to provide information on other chemicals in the urine such as albumin or protein.

Normal Values

Urine creatinine (24-hour sample) values can range from 500 to 2000 mg/day. Results depend greatly on your age and amount of lean body mass.

Another way of expressing the normal range for these test results are:

  • 14 to 26 mg per kg of body mass per day for men
  • 11 to 20 mg per kg of body mass per day for women

The examples above are common measurements for results of these tests. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test results.

What abnormal results mean

Abnormal results of urine creatinine are nonspecific, but may be due to any of the following conditions:

References

Landry DW, Bazari H. Approach to the patient with renal disease. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 116.


Review Date: 8/21/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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