Optic neuritis Definition
Optic neuritis is inflammation of the optic nerve. It may cause sudden, reduced vision in the affected eye.
Alternative Names Retro-bulbar neuritis Causes, incidence, and risk factors
The exact cause of optic neuritis is unknown.
The optic nerve carries visual informations from your eye to the brain. Sudden swelling of this nerve can damage the insulation (
myelin sheath) surrounding each nerve fiber. This can result in permanent visual loss.
Conditions that have been linked with optic neuritis include:
Autoimmune diseases, including lupus, sarcoidosis, and Behcet's disease
Cryptococcosis, a fungal infection
Bacterial infections, including tuberculosis, syphilis, Lyme disease, and meningitis
Viral infections, including viral encephalitis, measles, rubella, chickenpox, herpes zoster, mumps, and mononucleosis
Respiratory infections, including Mycoplasma pneumonia and common upper respiratory tract infections
Multiple sclerosis Symptoms Loss of vision in one eye over an hour or a few hours
Changes in the way the pupil reacts to bright light
Loss of color vision
Pain when you move the eye Signs and tests
A complete medical examination can help rule out related diseases. Tests may include:
Vision often returns to normal within 2 - 3 weeks with no treatment.
Corticosteroids given through a vein (IV) or taken by mouth may speed up recovery. Higher doses should be used cautiously, as they can have serious side effects.
Further tests may be needed to determine the cause of the neuritis. The condition causing the problem can then be treated.
People who have optic neuritis without a disease such as multiple sclerosis have a good chance of recovery.
Optic neuritis caused by
multiple sclerosis or other autoimmune diseases such as systemic lupus erythematosus has a poorer outlook. However, vision in the affected eye may still return to normal.
Complications Body-wide side effects from corticosteroids
About 1 in 5 patients with a first episode of optic neuritis will develop myelin sheath inflammation elsewhere in the body, or will develop multiple sclerosis.
Calling your health care provider
Call your health care provider immediately if you have a sudden loss of vision in one eye, especially if you have eye pain.
If you have been diagnosed with optic neuritis, call your health care provider if:
Your vision decreases
The pain in the eye gets worse
Your symptoms do not improve with treatment References
Glaser JS. Topical diagnosis: prechiasmal visual pathways. In: Tasman W, Jaeger EA, eds.
Duane’s Ophthalmology. 15th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2009:chap 5.
Sra SK, Sra KK, Friedlaender M, Trocme SD. Immunology of neurologic and endocrine diseases that affect the eye. In: Tasman W, Jaeger EA, eds.
Duane’s Ophthalmology. 15th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2009:chap 35.
David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc., and Franklin W. Lusby, MD, Ophthalmologist, Lusby Vision Institute, La Jolla, California.
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