Treatment begins with plenty of fluids and electrolytes. Replacement of folate, iron, vitamin B12, and other nutrients may also be needed. Antibiotic therapy with tetracycline or another broad-spectrum antibiotic is given at the beginning of treatment.
Oral tetracycline is usually not prescribed for children until after all of their permanent teeth have appeared, because it can permanently discolor teeth that are still forming. However, other antibiotics are available.
The outcome is good with treatment.
Vitamin and mineral deficiencies are common complications.
In children, sprue leads to:
Delay in the maturing of bones (skeletal maturation)
Tropical sprue symptoms get worse or do not improve with treatment
You develop new symptoms
You have diarrhea or other symptoms of this disorder for a long period of time, especially after spending time in the tropics
Other than avoiding living in or traveling to tropical climates, there is no known prevention for tropical sprue.
Semrad CE. Approach to the patient with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 142.
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.