Angiotensin-converting enzyme (ACE) inhibitors are medicines. They treat heart, blood vessel, and kidney problems.
How ACE Inhibitors Help You
ACE inhibitors are used to treat heart disease. These medicines make your heart work less hard. This keeps some kinds of heart disease from getting worse. Most people who have heart failure take these medicines.
These medicines treat high blood pressure, strokes, or heart attacks. They may help lower your risk for stroke or heart attack.
They also are used to treat diabetes and kidney problems. This can help keep your kidneys from getting worse. If you have these problems, ask your doctor if you should be taking these medicines.
Types of ACE Inhibitors
There are many different names and brands of ACE inhibitors. Most work as well as another. Side effects may be different for different ones.
Taking Your ACE Inhibitors
ACE inhibitors are pills that you take by mouth. Take all of your medicines as your doctor told you to. Try to take them at the same time, or times, each day. Do not stop taking your medicines without talking with your doctor first.
Follow up with your doctor regularly. Your doctor will check your blood pressure. Your doctor will also do blood tests to make sure the medicines are working properly. Your doctor may change your dose from time to time.
Plan ahead so that you do not run out of medicine. Make sure you have enough with you when you travel.
Other important tips are:
Before taking ibuprofen (Advil, Motrin) or aspirin, talk to your doctor.
Tell your doctor what other medicines you are taking. This includes anything you bought without a prescription, diuretics (water pills), potassium pills, or herbal or dietary supplements.
Do not take ACE inhibitors if you are pregnant or breastfeeding. Do not take these medicines if you are planning to become pregnant. Call your doctor if you become pregnant when you are taking these medicines.
Side effects from ACE inhibitors are rare.
You may have a dry cough. This may go away after a while. If it does not, tell your doctor. Sometimes reducing your dose helps. Do not lower your dose without talking with your doctor first.
You may feel dizzy or lightheaded when you start taking these medicines, or if your doctor increases your dose. Standing up slowly from a chair or your bed may help. If you have a fainting spell, call your doctor right away.
Some other side effects are:
Loss of appetite
Skin rashes or blisters
If your tongue or lips swell, call your doctor right away, or go to the emergency room. You may be having a serious allergic reaction to the medicine. This is very rare.
When to Call the Doctor
Call your doctor if you are having any of the side effects above. Also call your doctor if you are having other unusual symptoms.
American Diabetes Association. Standards of medical care in diabetes -- 2010. Diabetes Care. 2010; 33 Suppl 1:S11-S61.
Morrow, DA, Gersh BJ. Chronic coronary artery disease. In: Libby P, Bonow RO, Mann DL, Zipes DP, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 54.
Bernard J. Gersh
Jessup M, Abraham WT, Casey DE, Feldman AM, Francis GS, Ganiats TG, et al. 2009 focused update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation. 2009 Apr 14;119(14):1977-2016. Epub 2009 Mar 26.
A.D.A.M. Editorial: David Zieve, MD, MHA, and David R. Eltz. Previously reviewed by David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine (10/6/2010).