Carolinas HealthCare System

Research and Clinical Trials

CARE (Combating Antibiotic Resistance Enterobacteriaceae
Brief Description  
Patients with positive cultures for CRE (Cabapenem-Resistant Enterobacteriaceae) will be treated with either plazomicin or colistin (both with added meropenem or tigecycline) for up to 4 days. The study is looking to see if plazomicin is as good or better than the current treatment for CRE.
Who may be Eligible  
Ages 18-15; Positive culture for CRE; Not pregnant or breast feeding; Not have study defined prohibited co-infections; Not have antibiotic therapy for more than 72 hours prior to start; Not be on study disallowed mdications.
Start Date  
IRB Number  
Principal Investigator  
Horton, James
Contact Name  

For More Information, Contact   Jessica  A.  Kearney-Bryan , BSN
Phone:  (704) 355-0244  Fax:  (704) 446-7641 
Address:  1350 South Kings Drive
3rd Floor ID Clinic
Charlotte, NC 28207