Patient & Visitor Alert: Because flu cases are on the rise, starting February 24, children 12 and younger will be restricted from visiting hospitals and certain inpatient facilities throughout Carolinas HealthCare System. Learn more.
CARE (Combating Antibiotic Resistance Enterobacteriaceae
Patients with positive cultures for CRE (Cabapenem-Resistant Enterobacteriaceae) will be treated with either plazomicin or colistin (both with added meropenem or tigecycline) for up to 4 days. The study is looking to see if plazomicin is as good or better than the current treatment for CRE.
Who may be Eligible
Ages 18-15; Positive culture for CRE; Not pregnant or breast feeding; Not have study defined prohibited co-infections; Not have antibiotic therapy for more than 72 hours prior to start; Not be on study disallowed mdications.