Carolinas HealthCare System

Research and Clinical Trials

Title  
Cy4031
Brief Description  
The research study involves an investigational drug called tirasemtiv which is being investigated as a potential new therapy for the improvement of muscle weakness and muscle fatigue in patients with ALS (Amyotrophic Lateral Sclerosis). The purpose of the study is to assess the effect of tirasemtiv versus placebo on respiratory function but will also evaluate the safety, tolerability and efficacy of tirasemtiv when taken with or without riluzole. Time will be 60 weeks, 16 study visits.
Who may be Eligible  
Patients with familial or sporadic ALS diagnosed =24 months prior to screening who are =18 years of age.
Specialty/Disorder  
ALS - Amyotrophic Lateral Sclerosis
Start Date  
09/01/2015
IRB Number  
08-15-14B
Principal Investigator  
Brooks, Benjamin
Contact Name  
Cynthia

For More Information, Contact   Cynthia  Lary , RN
Phone:  (704) 446-6063  Fax:  (704) 446-1915 
Email:  cynthia.lary@carolinashealthcare.org
Address:  Neurosciences Institute, Neurology-Charlotte
1010 Edgehill Road North
Charlotte, NC 28207
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