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Carolinas HealthCare System

Research and Clinical Trials

Brief Description  
To find out if BG00012 (also known as Tecfidera or dimethyl fumarate) is effective in slowing the progression of disability in people with SPMS. The safety of BG00012, how well people tolerate it, and the effect it may have on the results of tests and evaluations used to assess SPMS. It will also look at the effect of BG00012 on biomarkers (naturally occuring substances in the body - e.g., proteins, ribonucleic acid {RNA} in the blood.
Who may be Eligible  
People with SPMS who are between 18 and 58 years of age ,and who have confirmed evidence of disease progression independent of clinical relapses over the 1 year prior to entry into the study.
MS - Multiple Sclerosis
Start Date  
IRB Number  
Principal Investigator  
Graves, Donna
Contact Name  

For More Information, Contact   Joyce  Pitner
Phone:  (704) 446-1349  Fax:  (704) 446-1915 
Address:  Carolinas Medical Center - Neurology
1010 Edgehill Road North
Charlotte, NC 28207