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What is the ACCORD-EYE Sub Study?

ACCORD-EYE is a research study to determine whether or not intensive therapy or control of blood glucose, blood pressure, and lipids will reduce the development and progression of diabetic retinopathy. Retinopathy associated with diabetes is the leading cause of acquired blindness in adults in the U.S. The ACCORD-EYE Study will involve a group of 4,065 people with diabetes already participating in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study, and is sponsored by The National Eye Institute and The National Heart, Lung and Blood Institute.

What is the purpose of ACCORD-EYE?

The purpose of this study is to investigate the effects of the ACCORD medical treatment (blood sugar control, blood pressure control and blood lipid control) on eye disease (diabetic retinopathy) in ACCORD participants, all of whom have diabetes.

Who can participate?

Men and women who are already participating in the ACCORD study who have not had either laser photocoagulation or vitrectomy in either eye are eligible for ACCORD-EYE. The ACCORD-EYE is a sub study to ACCORD and you do not have to volunteer for ACCORD-EYE to stay in ACCORD.

What is involved in participation?

Participants in the ACCORD-EYE Sub Study will have two eye exams with fundus (part of the retina, or the back of the eye) photographs taken. Eye exams occur at the start of the study and again in four years.

What are the benefits of participating?

An eye exam for patients with diabetes should be considered an essential part of medical care. Diabetic retinopathy requiring treatment may be identified on such study visits. There may be direct benefit in that the early diagnosis of retinopathy allows for the best chance to avoid blindness from diabetes. You will be notified of abnormalities and treatment options will be recommended to you and your doctors.

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